4Departments of Biological Sciences and Computing Science, University of Alberta, Edmonton, AB, Canada.3Department of Medicine, Division of Gastroenterology, McMaster University, Hamilton, ON, Canada.2Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.1Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada.Meera Shanmuganathan 1, Mohammad Omair Sarfaraz 2, Zachary Kroezen 1, Holly Philbrick 1, Richel Poon 1, Andrew Don-Wauchope 2, Marco Puglia 3, David Wishart 4 and Philip Britz-McKibbin 1*